Response by Parikh and Kamel to Letter Regarding Article, “Stroke Risk and Mortality in Patients With Ventricular Assist Devices”

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Response by Parikh and Kamel to Letter Regarding Article, "Stroke Risk and Mortality in Patients With Ventricular Assist Devices".

BACKGROUND AND PURPOSE Ventricular assist devices (VADs) have advanced the management of end-stage heart failure. However, these devices are associated with hemorrhagic and thrombotic complications, including stroke. We assessed the incidence, risk factors, and outcomes of ischemic and hemorrhagic stroke after VAD placement. METHODS Using administrative claims data from acute care hospitals i...

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Stroke Risk and Mortality in Patients With Ventricular Assist Devices

Ventricular assist devices (VADs) play an important role in the management of advanced heart failure. VAD therapy is intended for patients with severe heart failure that causes disabling symptoms such as dyspnea at rest or with minimal activity or such heart failure that requires inotrope therapy. VADs provide mechanical circulatory support to patients primarily as a bridge to heart transplanta...

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Letter by Jennings regarding article, "Mechanisms of bleeding and approach to patients with axial-flow left ventricular assist devices".

Axial-flow LVADs have become an integral tool in the management of end-stage heart failure. Consequently, nonsurgical bleeding has emerged as a major source of morbidity and mortality in this fragile population. The mechanisms responsible for these adverse events include acquired von Willebrand disease, GI tract angiodysplasia formation, impaired platelet aggregation, and overuse of anticoagula...

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Response to Letter by D'Anna et al regarding article, "Long-term mortality in patients with stroke of undetermined etiology".

BACKGROUND AND PURPOSE The determination of stroke etiology is essential for planning treatment for stroke prevention. However, the etiology of stroke is undetermined in many patients. METHODS During a 10-year period, consecutive patients with acute ischemic stroke were enrolled. The stroke etiology was determined based on the Trial of ORG 10172 in Acute Stroke Treatment classification. Long-...

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Response to Letter Regarding Article, "Patterns and Implications of Intracranial Arterial Remodeling in Stroke Patients".

Response to Letter Regarding Article, “Patterns and Implications of Intracranial Arterial Remodeling in Stroke Patients” We appreciate the opportunity to respond to comments by Gutierrez and Elkind about our recent article. We think that they misunderstood our imaging-based methodology and would like to offer reasons that might explain their discrepant results. The authors assert that plaque bu...

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ژورنال

عنوان ژورنال: Stroke

سال: 2017

ISSN: 0039-2499,1524-4628

DOI: 10.1161/strokeaha.116.015958